Oxlade-Chamberlain, Henderson and Salah were on target as Liverpool equalled City’s record for consecutive home league wins.
Liverpool continued their unbeaten run as a 4-0 victory over Southampton saw them open a 22-point gap at the top.
The Reds took a controversial lead through Alex Oxlade-Chamberlain’s shot just after the second half proceeded.
Henderson then teed up Salah to chip after Alisson’s precise long pass.
Salah then grabbed his second after Firmino’s unselfish assist set him up perfectly.
The brace saw Salah take his league tally to an impressive 14 goals so far.
The result puts Liverpool 22 points clear with second-placed Manchester City playing Tottenham on Sunday.
It also meant Liverpool had the biggest lead of any league leader in English football, according to Opta.
The win means Liverpool have taken 100 points from the last 102 available and leaves them unbeaten in the league in 394 days.