MANCHESTER, ENGLAND - NOVEMBER 01: Kevin De Bruyne of Manchester City goes down injured during the Carabao Cup Fourth Round match between Manchester City and Fulham at Etihad Stadium on November 1, 2018 in Manchester, England. (Photo by Michael Regan/Getty Images)

Manchester City have confirmed that Kevin De Bruyne will be out for the next 5-6 weeks with a knee injury

The Belgian midfielder sustained damage to his left knee in the 86th minute of City’s 2-0 Carabao Cup win over Fulham on Thursday.

This will come as a major blow for De Bruyne, considering he had only just returned from a three-month absence due to ligament damage to his right knee.

“The Belgian underwent scans on Friday at the CFA,” read a statement on the club website.

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The 22-year-old has been manager Marco Silva's first choice ahead of Turkey international Cenk Tosun in the English Premier League team.

“No surgery is needed but he is expected to be out for between 5-6 weeks.”

De Bruyne sustained another serious injury in January 2016 from his right knee and ankle ligaments.

The 27-year-old played an integral role in City’s Premier League title-winning campaign last season by contributing eight goals and 16 assists.

Pep Guardiola’s side will host Southampton at the Etihad Stadium this Sunday for a Premier League game.