The Russians are the leaders of Group E, with five points after three rounds, while their hosts today are third, one point behind.
Flashscore presents the key facts before the match:
Sevilla will be on a revenge mission when they face Spartak Moscow at the Ramon Sanchez Pizjuan. Eduardo Berizzo’s men are still smarting from the 5-1 thrashing by the Russian champions a fortnight ago, their heaviest European defeat in 59 Years.
Halfway through the Champions League (CL) group stages, Liverpool are top of a tight Group E, level on 5 points with Spartak and 1 clear of Sevilla. Maribor are rock-bottom with just 1 point.
Sevilla’s last home loss came in November 2016. The 5-time Europa League winners have gone a mind-boggling 23 domestic games unbeaten in all competitions (W16, D7).
The hosts have a decent home record against Russian teams (W4, L1).
Spartak have won fewer corners than any other side in the competition so far (3).
French striker Wissam Ben Yedder has been in impressive form this season, netting 8 goals in 11 appearances for Sevilla.
Sevilla: D. Carrico (thigh injury), N. Pareja (hip injury), Jose Mena (doubtful), G. Mercado (doubtful)
Spartak Moscow: J. Ananidze (ankle injury), A. Samedov (hip injury), G. Tigiev (knee injury), R. Zobnin (knee injury), A. Timofeev (doubtful), Ze Luis (doubtful).