4.- Sevilla CF
The first wild card of this list is the most successful football club in Europa League history. Sevilla FC is going to have a very complicated Round of 16 against AS Roma.
They have a major chance of losing this stage of the tournament but they will have all their previous experience to help them prevail. We will give them the edge only because they already have a long history in this competition.
Sevilla FC is going to try to win the fifth title in their long history, five of them have been in the new millennium.