English side have had to endure a tough period following their second exit from a cup competition in the space of four days.
The London side is set to have a relief as Son Heung-Min is believed to likely return for their midweek clash with Watford.
Son has missed the last three games while being on international duty with South Korea at the Asian Cup, but their surprise quarter-final exit to Qatar means he is back in the fold earlier than expected.
“On Sunday we were with him on the training ground in the morning,” boss Mauricio Pochettino SportBT.
“He’s so tired, he played three games. Very tough games.
“Of course not too much energy on Sunday, but we hope he’ll be available and ready on Wednesday to help the team.”
Pochettino says he has moved on from the defeats and has shifted his focus on a top four finish in the Premier league as well as advancing in the UEFA champions league.
“Of course I am disappointed because, after Thursday and today again, out of two competitions – you feel disappointed. You can’t feel anything different,” Pochettino said.
“But now we have to be positive. We are still in two competitions, in a good position in the Premier League and the Champions League is a massive motivation for the whole club. We have to be strong.
“Now the realistic targets are trying to be in the top four, try and be close to Manchester City and Liverpool and reduce the gap.
“To be a contender is always difficult for us. (Top four) is realistic.
“Another is to try and beat (Borussia) Dortmund and be in the next round of the Champions League. That is tough.”